February 3, 2005 — The FDA regulation, introduced Oct, 2004, requiring a black box warning that all antidepressants increase the risk of suicidal thinking and behavior in children and adolescents and a warning must be cited in all advertising as well as included in the package insert, is finalized.

Dec 26, 2005 — An unusually high quality new blog appears under the title "1boringoldman". It starts out with primarily political commentary. As time goes on, the anonymous author is revealed to have medical knowledge and detailed understanding of events related to drug safety and conflicts of interest.